Infectious mononucleosis prior to acute leukemia: A possible role for the epstein-barr virus

Epstein–Barr virus (EBV) is estimated to infect more than 98% of adults worldwide and is one of the most common human viruses. Acute acalculous cholecystitis (AAC) of the gallbladder is an atypical complication of infectious mononucleosis caused by EBV. Conservative management has been described in the context of AAC caused by EBV. A surgical approach must be considered in the case of acute complications such as perforation or gallbladder gangrene. We present the case of a 10-year-old female patient with AAC due to infectious mononucleosis syndrome caused by primary EBV infection.

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Parvovirus B19 Mimicking Epstein-Barr Virus Infectious Mononucleosis in an Adult

The American Journal of Medicine ◽

10.1016/j.amjmed.2012.12.010 ◽

2013 ◽

Vol 126 (5) ◽

pp. e7-e8 ◽

Cited By ~ 1

Author(s):

Sigridh Muñoz-Gómez ◽

Burke A. Cunha

Keyword(s):

Infectious Mononucleosis ◽

Epstein Barr Virus ◽

Parvovirus B19 ◽

Barr Virus ◽

Epstein Barr

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Infectious Mononucleosis With Epstein-Barr Virus Antibodies in Older Ages

JAMA ◽

10.1001/jama.1968.03140340065021 ◽

1968 ◽

Vol 205 (8) ◽

pp. 595

Author(s):

Richard L. Golden

Keyword(s):

Infectious Mononucleosis ◽

Epstein Barr Virus ◽

Barr Virus ◽

Epstein Barr

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Epstein-Barr Virus Is Not Synonymous With Infectious Mononucleosis

PEDIATRICS ◽

10.1542/peds.61.3.506a ◽

1978 ◽

Vol 61 (3) ◽

pp. 506-506

Author(s):

Alex J. Steigman

Keyword(s):

Infectious Mononucleosis ◽

Primary Infection ◽

Epstein Barr Virus ◽

Clinical Syndrome ◽

Barr Virus ◽

Clinical Responses ◽

Epstein Barr ◽

Uncertain Etiology

Infectious mononucleosis (IM) is a defined clinical syndrome, until recently regarded as of uncertain etiology affecting only a limited number of persons. The etiology of IM can now be ascribed correctly to primary infection with Epstein-Barr virus (EBV), a member of the herpesvirus family. It is increasingly evident that primary infection with EBV may also induce a range of clinical responses from no detectable illness1 to a variety of disorders without the clinical or hematologic hallmarks of the IM syndrome.

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Fatal Septic Shock in a Patient with Hemophagocytic Lymphohistiocytosis Associated with an Infectious Mononucleosis

Case Reports in Critical Care ◽

10.1155/2018/9756050 ◽

2018 ◽

Vol 2018 ◽

pp. 1-4 ◽

Cited By ~ 1

Author(s):

Giorgio Berlot ◽

Ariella Tomasini ◽

Lorenzo Zandonà ◽

Eugenio Leonardo ◽

Rossana Bussani ◽

...

Keyword(s):

Septic Shock ◽

Infectious Mononucleosis ◽

Hemophagocytic Lymphohistiocytosis ◽

Epstein Barr Virus ◽

Multiple Organ ◽

Aggressive Lymphoma ◽

Systemic Involvement ◽

Barr Virus ◽

Epstein Barr ◽

Clinical Pictures

The authors describe the case of a young woman who developed a clinical pictures resembling a septic shock-related multiple organ dysfunction syndrome a couple of months after having been diagnosed suffering from a hemophagocytic lymphohistiocytosis associated with an infectious mononucleosis. Despite the aggressive treatment, which included antibiotics, vasopressors, IV immunoglobulins, and the use of an extracorporeal device aimed to remove mediators released both during sepsis and the cytokine storm determined by the hemophagocytic lymphohistiocytosis, the patient died. At the autopsy, an extremely uncommon aggressive lymphoma of Epstein-Barr virus-positive T-lymphocytes with systemic involvement was discovered.

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